The laboratory tests and host immunity of COVID-19 patients with different severity of illness

BACKGROUNDThe coronavirus disease 2019 (COVID-19), infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a severe outbreak throughout the world. The host immunity of COVID-19 patients is unknown.METHODSThe routine laboratory tests and host immunity in COVID-19 patients with different severity of illness were compared after patient admission.RESULTSA total of 65 SARS-CoV-2-positive patients were classified as having mild (n = 30), severe (n = 20), and extremely severe (n = 15) illness. Many routine laboratory tests, such as ferritin, lactate dehydrogenase, and D-dimer, were increased in severe and extremely severe patients. The absolute numbers of CD4+ T cells, CD8+ T cells, and B…

• FR
  Fundamental Research Funds for the Central Universities

  Award: 2019kfyRCPY098
• NM
  National Mega Project on Major Infectious Disease Prevention

  Awards: 2017ZX10103005, 2017ZX10103005-007