COVID-19: ICU delirium management during SARS-CoV-2 pandemic
Pomeranian Medical University · Vanderbilt University · +3 more institutions
Abstract
The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19), emerged as a public health threat in December 2019 and was declared a pandemic by the World Health Organization in March 2020. Delirium, a dangerous untoward prognostic development, serves as a barometer of systemic injury in critical illness. The early reports of 25% encephalopathy from China are likely a gross underestimation, which we know occurs whenever delirium is not monitored with a valid tool. Indeed, patients with COVID-19 are at accelerated risk for delirium due to at least seven factors including (1) direct central nervous system (CNS) invasion, (2) induction of CNS inflammatory mediators, (3) secondary effect of other…
Citation impact
- FWCI
- 53.62
- Percentile
- 100%
- References
- 88
Authors
6- KKKatarzyna KotfisCorresponding
Pomeranian Medical University
- SWShawniqua Williams Roberson
Vanderbilt University, Vanderbilt University Medical Center
- JEJo Ellen Wilson
Geriatric Research Education and Clinical Center, Vanderbilt University Medical Center
- WDWojciech Dąbrowski
Medical University of Lublin
- BTBrenda T. Pun
Vanderbilt University Medical Center
Topics & keywords
- Medicine
- Delirium
- Intensive care medicine
- Intensive care unit
- Pandemic
- Mechanical ventilation
- Intensive care
- Psychological intervention
- Good health and well-being
Funding
- ELEli Lilly and Company
- PPfizer
- VUVanderbilt University
- VUVanderbilt University Medical Center
- NINational Institute on AgingAwards: KL2TR002245, R01AG058639
- NHNational Heart, Lung, and Blood InstituteAward: R01HL14678-01
- NINational Institute of General Medical SciencesAward: R01GM120484
- NCNational Center for Advancing Translational SciencesAward: KL2TR002245