The many faces of the anti-COVID immune response
Memorial Sloan Kettering Cancer Center · Parker Institute for Cancer Immunotherapy · +2 more institutions
Indexed incrossrefpubmed
Abstract
The novel 2019 strain of coronavirus is a source of profound morbidity and mortality worldwide. Compared with recent viral outbreaks, COVID-19 infection has a relatively high mortality rate, the reasons for which are not entirely clear. Furthermore, treatment options for COVID-19 infection are currently limited. In this Perspective, we explore the contributions of the innate and adaptive immune systems to both viral control as well as toxicity during COVID-19 infections and offer suggestions to both understand and therapeutically modulate anti-COVID immunity.
Citation impact
539
total citations
- FWCI
- 12.87
- Percentile
- 100%
- References
- 108
Citations per year
Authors
2Topics & keywords
Topics
Keywords
- Coronavirus disease 2019 (COVID-19)
- Immune system
- Acquired immune system
- Coronavirus
- Outbreak
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- 2019-20 coronavirus outbreak
- Immunity
UN Sustainable Development Goals
- Good health and well-being
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