Metal–Organic Framework Nanocarriers for Drug Delivery in Biomedical Applications
Hunan University · University of Florida Health · +9 more institutions
Abstract
Investigation of metal-organic frameworks (MOFs) for biomedical applications has attracted much attention in recent years. MOFs are regarded as a promising class of nanocarriers for drug delivery owing to well-defined structure, ultrahigh surface area and porosity, tunable pore size, and easy chemical functionalization. In this review, the unique properties of MOFs and their advantages as nanocarriers for drug delivery in biomedical applications were discussed in the first section. Then, state-of-the-art strategies to functionalize MOFs with therapeutic agents were summarized, including surface adsorption, pore encapsulation, covalent binding, and functional molecules as building blocks. In the third section,…
Citation impact
- FWCI
- 30.93
- Percentile
- 100%
- References
- 179
Authors
10- YSYujia SunCorresponding
Hunan University, University of Florida Health, Interface (United States), University of Florida, UF Health Cancer Center, State Key Laboratory of Chemobiosensing and Chemometrics
- LZLiwei Zheng
Stanford University
- YYYu Yang
University of Florida Health, Interface (United States), University of Florida, State Key Laboratory of Oncogene and Related Genes, UF Health Cancer Center
- XQXu Qian
Cancer Hospital of Chinese Academy of Medical Sciences, University of Chinese Academy of Sciences
- TFTing Fu
Hunan University, Cancer Hospital of Chinese Academy of Medical Sciences, State Key Laboratory of Chemobiosensing and Chemometrics
Topics & keywords
- Nanocarriers
- Nanotechnology
- Drug delivery
- Metal-organic framework
- Aptamer
- Surface modification
- Materials science
- Context (archaeology)
- Good health and well-being