articleFrontiers in MicrobiologyJul 22, 2020GOLD OA

Geographic and Genomic Distribution of SARS-CoV-2 Mutations

DMDaniele MercatelliFMFederico M. Giorgi

University of Bologna

PubMed
Indexed incrossrefdoajpubmed

Abstract

The novel respiratory disease COVID-19 has reached the status of worldwide pandemic and large efforts are currently being undertaken in molecularly characterizing the virus causing it, SARS-CoV-2. The genomic variability of SARS-CoV-2 specimens scattered across the globe can underly geographically specific etiological effects. In the present study, we gather the 48,635 SARS-CoV-2 complete genomes currently available thanks to the collection endeavor of the GISAID consortium and thousands of contributing laboratories. We analyzed and annotated all SARS-CoV-2 mutations compared with the reference Wuhan genome NC_045512.2, observing an average of 7.23 mutations per sample. Our analysis shows the prevalence of…

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Topics & keywords

Topics
Keywords
  • Clade
  • Genome
  • Biology
  • Pandemic
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Mutation
  • Coronavirus disease 2019 (COVID-19)
  • Genetics
UN Sustainable Development Goals
  • Good health and well-being
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