Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019

AIMS: To investigate the characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019 (COVID-19). METHODS AND RESULTS: We enrolled 671 eligible hospitalized patients with severe COVID-19 from 1 January to 23 February 2020, with a median age of 63 years. Clinical, laboratory, and treatment data were collected and compared between patients who died and survivors. Risk factors of death and myocardial injury were analysed using multivariable regression models. A total of 62 patients (9.2%) died, who more often had myocardial injury (75.8% vs. 9.7%; P

• NN
  National Natural Science Foundation of China

  Awards: 81770324, 81800447, 2016ACA153, 2017CFB204
• NS
  Natural Science Foundation of Hubei Province

  Awards: 2017CFB204, 81800447