reviewFrontiers in MicrobiologyMay 21, 2020GOLD OA

Beyond Risk: Bacterial Biofilms and Their Regulating Approaches

Fujian Agriculture and Forestry University · Ministry of Education

PubMed
Indexed incrossrefdoajpubmed

Abstract

Bacterial biofilms are complex surface attached communities of bacteria held together by self-produced polymer matrixs mainly composed of polysaccharides, secreted proteins, and extracellular DNAs. Bacterial biofilm formation is a complex process and can be described in five main phases: (i) reversible attachment phase, where bacteria non-specifically attach to surfaces; (ii) irreversible attachment phase, which involves interaction between bacterial cells and a surface using bacterial adhesins such as fimbriae and lipopolysaccharide (LPS); (iii) production of extracellular polymeric substances (EPS) by the resident bacterial cells; (iv) biofilm maturation phase, in which bacterial cells synthesize and release…

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