articleBloodJun 3, 2020BRONZE OA

COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection

Harvard University · Massachusetts General Hospital · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Patients with coronavirus disease 2019 (COVID-19) have elevated D-dimer levels. Early reports describe high venous thromboembolism (VTE) and disseminated intravascular coagulation (DIC) rates, but data are limited. This multicenter retrospective study describes the rate and severity of hemostatic and thrombotic complications of 400 hospital-admitted COVID-19 patients (144 critically ill) primarily receiving standard-dose prophylactic anticoagulation. Coagulation and inflammatory parameters were compared between patients with and without coagulation-associated complications. Multivariable logistic models examined the utility of these markers in predicting coagulation-associated complications, critical illness,…

Citation impact

1,397
total citations
FWCI
31.69
Percentile
100%
References
22
Citations per year

Authors

13

Topics & keywords

Keywords
  • Coronavirus disease 2019 (COVID-19)
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Medicine
  • 2019-20 coronavirus outbreak
  • Coagulation
  • Betacoronavirus
  • Virology
  • Pandemic
UN Sustainable Development Goals
  • Good health and well-being
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