reviewChemical ReviewsMay 29, 2020GREEN OA

Catalytic Enantioselective Ring-Opening Reactions of Cyclopropanes

VPVincent PirenneBMBastian MurielJWJérôme Waser

École Polytechnique Fédérale de Lausanne

PubMed
Indexed incrossrefpubmed

Abstract

This review describes the development of enantioselective methods for the ring opening of cyclopropanes. Both approaches based on the reaction of nonchiral cyclopropanes and (dynamic) kinetic resolutions and asymmetric transformations of chiral substrates are presented. The review is organized according to substrate classes, starting by the more mature field of donor-acceptor cyclopropanes. Emerging methods for enantioselective ring opening of acceptor- or donor-only cyclopropanes are then presented. The last part of the review describes the ring opening of more reactive three-membered rings substituted with unsaturations with a particular focus on vinylcyclopropanes, alkylidenecyclopropanes, and…

Citation impact

544
total citations
FWCI
30.37
Percentile
100%
References
169
Citations per year

Authors

3

Topics & keywords

Topics
Keywords
  • Enantioselective synthesis
  • Chemistry
  • Ring (chemistry)
  • Substrate (aquarium)
  • Catalysis
  • Combinatorial chemistry
  • Stereochemistry
  • Organic chemistry
No related works found for this paper.

Funding