articleNucleic Acids ResearchMay 22, 2020GOLD OA

miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology

McGill University

PubMed
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Abstract

MiRNet is an easy-to-use, web-based platform designed to help elucidate microRNA (miRNA) functions by integrating users' data with existing knowledge via network-based visual analytics. Since its first release in 2016, miRNet has been accessed by >20 000 researchers worldwide, with ∼100 users on a daily basis. While version 1.0 was focused primarily on miRNA-target gene interactions, it has become clear that in order to obtain a global view of miRNA functions, it is necessary to bring other important players into the context during analysis. Driven by this concept, in miRNet version 2.0, we have (i) added support for transcription factors (TFs) and single nucleotide polymorphisms (SNPs) that affect miRNAs,…

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Authors

4

Topics & keywords

Keywords
  • Biology
  • Workflow
  • microRNA
  • Computational biology
  • Context (archaeology)
  • Gene regulatory network
  • Visual analytics
  • Interface (matter)
UN Sustainable Development Goals
  • Industry, innovation and infrastructure
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