Visible Light-Driven Radical-Mediated C–C Bond Cleavage/Functionalization in Organic Synthesis

Thermal C-C bond cleavage reactions allow the construction of structurally diverse molecular skeletons via predictable and efficient bond reorganizations. Visible light photoredox-catalyzed radical-mediated C-C bond cleavage reactions have recently emerged as a powerful alternative method for overcoming the thermodynamic and kinetic barrier of C-C bond cleavage in diverse molecular scaffolds. In recent years, a plethora of elegant and useful reactions have been invented, and the products are sometimes otherwise inaccessible by classic thermal reactions. Considering the great influence and synthetic potential of these reactions, we provide a summary of the state of art visible light-driven radical-mediated C-C…

• NN
  National Natural Science Foundation of China

  Awards: 91856119, 21772053, 91956201, 21622201, 21971081, 21820102003
• MO
  Ministry of Education of the People's Republic of China

  Awards: CCNU19TS051, B17019
• SA
  State Administration of Foreign Experts Affairs

  Award: B17019
• DO
  Department of Science and Technology, Hubei Provincial People's Government

  Award: 2017AHB047