Piezocatalytic Tumor Therapy by Ultrasound‐Triggered and BaTiO 3 ‐Mediated Piezoelectricity
Chinese Academy of Sciences · Shanghai Institute of Ceramics · +1 more institution
Abstract
Abstract Ultrasound theranostics features non‐invasiveness, minor energy attenuation, and high tissue‐penetrating capability, and is playing ever‐important roles in the diagnosis and therapy of diseases in clinics. Herein, ultrasound is employed as a microscopic pressure resource to generate reactive oxygen species (ROS) for piezocatalytic tumor therapy under catalytic mediation by piezoelectric tetragonal BaTiO 3 (T‐BTO). Under the ultrasonic vibration, the electrons and holes are unpaired and they are separated by the piezoelectricity, resulting in the establishment of a strong built‐in electric field, which subsequently catalyzes the generation of ROS such as toxic hydroxyl ( • OH) and superoxide radicals (…
Citation impact
- FWCI
- 24.56
- Percentile
- 100%
- References
- 49
Authors
3- PZPiao Zhu
Chinese Academy of Sciences, Shanghai Institute of Ceramics, University of Chinese Academy of Sciences
- YCYu ChenCorresponding
Chinese Academy of Sciences, Shanghai Institute of Ceramics, University of Chinese Academy of Sciences
- JSJianlin ShiCorresponding
Chinese Academy of Sciences, Shanghai Institute of Ceramics
Topics & keywords
- Materials science
- Reactive oxygen species
- Sonodynamic therapy
- In vivo
- Piezoelectricity
- Ultrasound
- Nanotechnology
- Nanoparticle