Bat-borne virus diversity, spillover and emergence

Most viral pathogens in humans have animal origins and arose through cross-species transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus, Nipah virus, Hendra virus, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory coronavirus (MERS-CoV) and SARS-CoV-2, have been linked back to various bat species. Despite decades of research into bats and the pathogens they carry, the fields of bat virus ecology and molecular biology are still nascent, with many questions largely unexplored, thus hindering our ability to anticipate and prepare for the next viral outbreak. In this Review, we discuss the latest advancements and understanding of bat-borne…

• US
  United States Agency for International Development
• NI
  National Institutes of Health

  Award: R01AI110964
• DA
  Defense Advanced Research Projects Agency

  Award: D18AC00031
• DT
  Defense Threat Reduction Agency

  Award: HDTRA11710064
• NI
  National Institute of Allergy and Infectious Diseases

  Award: R01AI110964