reviewCritical CareJun 18, 2020GOLD OA

The unique characteristics of COVID-19 coagulopathy

TIToshiaki IbaJHJerrold H. LevyJMJean M. ConnorsTETheodore E. WarkentinJTJecko Thachil

Juntendo University · Duke University · +6 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Thrombotic complications and coagulopathy frequently occur in COVID-19. However, the characteristics of COVID-19-associated coagulopathy (CAC) are distinct from those seen with bacterial sepsis-induced coagulopathy (SIC) and disseminated intravascular coagulation (DIC), with CAC usually showing increased D-dimer and fibrinogen levels but initially minimal abnormalities in prothrombin time and platelet count. Venous thromboembolism and arterial thrombosis are more frequent in CAC compared to SIC/DIC. Clinical and laboratory features of CAC overlap somewhat with a hemophagocytic syndrome, antiphospholipid syndrome, and thrombotic microangiopathy. We summarize the key characteristics of representative…

Citation impact

549
total citations
FWCI
75.45
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100%
References
59
Citations per year

Authors

6

Topics & keywords

Topics
Keywords
  • Medicine
  • Coronavirus disease 2019 (COVID-19)
  • Coagulopathy
  • 2019-20 coronavirus outbreak
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Pandemic
  • Intensive care medicine
  • Virology
UN Sustainable Development Goals
  • Good health and well-being
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