Cervical cancer in low and middle‑income countries (Review)
University of Pretoria · South African Medical Research Council · +9 more institutions
Abstract
Cervical cancer is a malignant tumour that occurs in the cervix and is classified into two histological types, adenocarcinoma and squamous cell carcinoma (SCC); SCC is more common and accounts for 70% of all cases. In 2018 there were ~569,000 new cases of cervical cancer diagnosed worldwide and ~311,000 deaths were attributed to cervical cancer. Of these, between 84 and 90% occurred in low- and middle-income countries (LMICs) such as South Africa, India, China and Brazil. The most common cause of cervical cancer is persistent infection caused by the sexually transmitted human papilloma virus. Other factors that contribute to the incidence of cervical cancer include geography, traditional practices and beliefs,…
Citation impact
- FWCI
- 28.39
- Percentile
- 100%
- References
- 157
Authors
11- RHRodney HullCorresponding
University of Pretoria, South African Medical Research Council
- MMMzwandile Mbele
University of Pretoria, South African Medical Research Council
- TJTshepiso J. Makhafola
South African Medical Research Council, University of Pretoria
- CHChindo Hicks
Louisiana State University, Louisiana State University Health Sciences Center New Orleans
- SWShaoming Wang
Chinese Academy of Medical Sciences & Peking Union Medical College
Topics & keywords
- Cancer
- Cervical cancer
- Low and middle income countries
- Molecular medicine
- Medicine
- Oncogene
- Developing country
- Cell cycle
- Good health and well-being