Protein-Based Nanoparticles as Drug Delivery Systems
Kangwon National University · Harvard University · +6 more institutions
Abstract
Nanoparticles have been extensively used as carriers for the delivery of chemicals and biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural biomolecules, such as proteins, are an attractive alternative to synthetic polymers commonly used in nanoparticle formulation because of their safety. In general, protein nanoparticles offer many advantages, such as biocompatibility and biodegradability. Moreover, the preparation of protein nanoparticles and the corresponding encapsulation process involved mild conditions without the use of toxic chemicals or organic solvents. Protein nanoparticles can be generated using proteins, such as fibroins, albumin, gelatin, gliadine, legumin, 30Kc19,…
Citation impact
- FWCI
- 20.87
- Percentile
- 100%
- References
- 170
Authors
6- SHSeyoung Hong
Kangwon National University
- DWDong Wook Choi
Harvard University, Dana-Farber Cancer Institute
- HNHong Nam Kim
Korea Institute of Brain Science, Korean Association Of Science and Technology Studies, Korea Institute of Science and Technology
- CGChun Gwon ParkCorresponding
Sungkyunkwan University
- WLWonhwa LeeCorresponding
Korea Research Institute of Bioscience and Biotechnology
Topics & keywords
- Nanoparticle
- Gelatin
- Biocompatibility
- Biomolecule
- Chemistry
- Drug delivery
- Emulsion
- Nanotechnology