reviewThe Lancet Infectious DiseasesJul 3, 2020BRONZE OA

Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics

European Society of Clinical Microbiology and Infectious Diseases · Aarhus University · +11 more institutions

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Abstract

The objective of this Personal View is to compare transmissibility, hospitalisation, and mortality rates for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with those of other epidemic coronaviruses, such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), and pandemic influenza viruses. The basic reproductive rate (R 0 ) for SARS-CoV-2 is estimated to be 25 (range 18-36) compared with 20-30 for SARS-CoV and the 1918 influenza pandemic, 09 for MERS-CoV, and 15 for the 2009 influenza pandemic. SARS-CoV-2 causes mild or asymptomatic disease in most cases; however, severe to critical illness occurs in a small proportion of infected…

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