articleMolecular Medicine ReportsDec 1, 2006GREEN OA

The innovation value chain

SRStephen RoperJDJun DuJHJames H. Love

Abstract

Wear particles generated between the interface of joints and artificial joint replacements are one of the primary causes of aseptic loosening. The aim of the present study was to investigate the influence of titanium (Ti) particles on the apoptosis and autophagy of osteoblasts, and probe into the potential use of hyperoside (Hy) as a protector for osteoblasts in Ti particle‑induced injury. MC3T3‑E1 cells were divided into control, Ti, Hy‑1+Ti and Hy‑2+Ti groups. Cell viability was detected using a Cell Counting Kit‑8 assay. Apoptosis and autophagy rates were determined using flow cytometry. Expression levels of apoptosis‑associated genes, including caspase‑3, apoptosis regulator BAX, apoptosis regulator Bcl‑2…

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739
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FWCI
45.37
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100%
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59
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Authors

3

Topics & keywords

Topics
Keywords
  • Complementarity (molecular biology)
  • Business
  • Industrial organization
  • Product innovation
  • Productivity
  • Value chain
  • Value (mathematics)
  • Knowledge value chain
UN Sustainable Development Goals
  • Decent work and economic growth
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