NCCN Guidelines Insights: Rectal Cancer, Version 6.2020

The NCCN Guidelines for Rectal Cancer provide recommendations for the diagnosis, evaluation, treatment, and follow-up of patients with rectal cancer. These NCCN Guidelines Insights summarize the panel discussion behind recent important updates to the guidelines. These updates include clarifying the definition of rectum and differentiating the rectum from the sigmoid colon; the total neoadjuvant therapy approach for localized rectal cancer; and biomarker-targeted therapy for metastatic colorectal cancer, with a focus on new treatment options for patients with BRAF V600E- or HER2 amplification-positive disease.

• RP
  Roswell Park Cancer Institute
• BA
  Brigham and Women's Hospital
• MG
  Massachusetts General Hospital
• VU
  Vanderbilt University
• UO
  University of Pennsylvania
• OS
  Ohio State University
• MS
  Memorial Sloan-Kettering Cancer Center
• VC
  Vanderbilt-Ingram Cancer Center
• CC
  Cleveland Clinic
• UO
  University of Utah
• JH
  Johns Hopkins University
• UO
  University of Wisconsin Carbone Cancer Center
• CC
  Case Comprehensive Cancer Center, Case Western Reserve University
• MC
  Moffitt Cancer Center
• HC
  Huntsman Cancer Institute
• OS
  Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
• NC
  National Comprehensive Cancer Network
• AJ
  Alvin J. Siteman Cancer Center
• MC
  Moores Cancer Center, UC San Diego Health
• HS
  Health Science Center, University of Tennessee
• UO
  University of Texas MD Anderson Cancer Center
• UO
  University of California, San Diego
• SK
  Sidney Kimmel Comprehensive Cancer Center
• CC
  Cancer Center, University of Colorado
• DC
  Duke Cancer Institute
• SC
  Stanford Cancer Institute