reviewRSC AdvancesJan 1, 2020GOLD OA

A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems

Zhengzhou University · Zhengzhou Children's Hospital · +7 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Drug delivery technology has a wide spectrum, which is continuously being upgraded at a stupendous speed. Different fabricated nanoparticles and drugs possessing low solubility and poor pharmacokinetic profiles are the two major substances extensively delivered to target sites. Among the colloidal carriers, nanolipid dispersions (liposomes, deformable liposomes, virosomes, ethosomes, and solid lipid nanoparticles) are ideal delivery systems with the advantages of biodegradation and nontoxicity. Among them, nano-structured lipid carriers and solid lipid nanoparticles (SLNs) are dominant, which can be modified to exhibit various advantages, compared to liposomes and polymeric nanoparticles. Nano-structured lipid…

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