Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents

Wu, Luling; Huang, Chusen; Emery, Ben P.; Sedgwick, Adam C.; Bull, Steven D.; He, Xiao‐Peng; Tian, He; Yoon, Juyoung; Sessler, Jonathan L.; James, Tony D.

doi:10.1039/c9cs00318e

reviewChemical Society ReviewsJan 1, 2020HYBRID OA

Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents

LWLuling Wu CHChusen Huang BPBen P. Emery ACAdam C. Sedgwick SDSteven D. Bull

Shanghai Normal University · University of Bath · +5 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

In this tutorial review, we will explore recent advances in the construction and application of Förster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.

Citation impact

973

total citations

FWCI: 54.62
Percentile: 100%
References: 50

Citations per year

Authors

10

Topics & keywords

Topics

Keywords

Förster resonance energy transfer
Energy transfer
Fluorescence
Chemistry
Nanotechnology
Resonance (particle physics)
Molecule
Chemical physics

UN Sustainable Development Goals

Affordable and clean energy

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