miRNA-based biomarkers, therapies, and resistance in Cancer
Central South University · Second Xiangya Hospital of Central South University · +1 more institution
Abstract
MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in size, play important roles in gene regulation, and their dysregulation is implicated in human diseases including cancer. A variety of miRNAs could take roles in the cancer progression, participate in the process of tumor immune, and function with miRNA sponges. During the last two decades, the connection between miRNAs and various cancers has been widely researched. Based on evidence about miRNA, numerous potential cancer biomarkers for the diagnosis and prognosis have been put forward, providing a new perspective on cancer screening. Besides, there are several miRNA-based therapies among different cancers being conducted, advanced…
Citation impact
- FWCI
- 20.15
- Percentile
- 100%
- References
- 256
Authors
11- BHBoxue He
Central South University, Second Xiangya Hospital of Central South University
- ZZZhenyu Zhao
Central South University, Second Xiangya Hospital of Central South University
- QCQidong Cai
Central South University, Second Xiangya Hospital of Central South University
- YZYuqian Zhang
Central South University, Second Xiangya Hospital of Central South University
- PZPengfei Zhang
Central South University, Second Xiangya Hospital of Central South University
Topics & keywords
- microRNA
- Cancer
- Bioinformatics
- Medicine
- Computational biology
- Biology
- Gene
- Internal medicine
- Good health and well-being