Molecular Engineering of NIR‐II Fluorophores for Improved Biomedical Detection
Fudan University · Collaborative Innovation Center of Chemistry for Energy Materials
Abstract
The development of fluorophores for the second near-infrared window (NIR-II, 1000-1700 nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical biology, and biomedical engineering. The wavelength, brightness, and stability are three crucial factors that determine the performance of an NIR-II fluorophore. Up to now, significant progress has been made in the development of NIR-II fluorescence molecular probes, including the synthesis of D-A-D and D-π-A fluorophores with improved NIR-II fluorescence imaging performance and the construction of off-on probes and ratiometric probes via energy transfer or molecular structure modification. In this review, we summarize the most recent…
Citation impact
- FWCI
- 29.27
- Percentile
- 100%
- References
- 163
Authors
2Topics & keywords
- Fluorophore
- Nanotechnology
- Molecular engineering
- Fluorescence
- Near-infrared spectroscopy
- Förster resonance energy transfer
- Energy transfer
- Materials science
- Affordable and clean energy
Funding
- NNNational Natural Science Foundation of ChinaAward: 21725502, 22088101, 51961145403, 21904023, 21908030,
- MOMinistry of Science and Technology of the People's Republic of ChinaAward: 2017YFA0207303
- SAScience and Technology Commission of Shanghai MunicipalityAward: 20JC1411700, 19490713100, 20490710600, 20S31903700