Oxidase-like MOF-818 Nanozyme with High Specificity for Catalysis of Catechol Oxidation
Jilin University · Chinese Academy of Sciences · +2 more institutions
Abstract
Despite the extensive studies of the nanozymes showing their superior properties compared to natural enzymes and traditional artificial enzymes, the development of highly specific nanozymes is still a challenge. The catechol oxidase specifically catalyzing the oxidations of o-diphenol to the corresponding o-quinone is important to the biosynthesis of melanin and other polyphenolic natural products. In this study, we first propose that MOF-818, containing trinuclear copper centers mimicking the active sites of natural catechol oxidase, shows efficient catechol oxidase activity with good specificity and no peroxidase-like characteristics. MOF-818 has good specificity and high catalytic activity as a novel…
Citation impact
- FWCI
- 20.77
- Percentile
- 100%
- References
- 43
Authors
5- MLMinghua Li
Jilin University, Chinese Academy of Sciences, Changchun Institute of Applied Chemistry
- JCJinxing Chen
University of Science and Technology of China, Chinese Academy of Sciences, Changchun Institute of Applied Chemistry
- WWWeiwei Wu
University of Science and Technology of China, Chinese Academy of Sciences, Changchun Institute of Applied Chemistry
- YFYouxing FangCorresponding
Chinese Academy of Sciences, Changchun Institute of Applied Chemistry
- SDShaojun DongCorresponding
University of Science and Technology of China, Jilin University, Chinese Academy of Sciences, Changchun Institute of Applied Chemistry
Topics & keywords
- Chemistry
- Catechol
- Catechol oxidase
- Polyphenol oxidase
- Enzyme
- Peroxidase
- Catalysis
- Oxidase test
- Clean water and sanitation