Ferroptosis: machinery and regulation
Southwestern Medical Center · Southwestern Medical Center · +3 more institutions
Abstract
2ME: beta-mercaptoethanol; α-KG: α-ketoglutarate; ccRCC: clear cell renal cell carcinoma; EMT: epithelial-mesenchymal transition; FAO: fatty acid beta-oxidation; GSH: glutathione; MEFs: mouse embryonic fibroblasts; MUFAs: monounsaturated fatty acids; NO: nitric oxide; NOX: NADPH oxidase; PPP: pentose phosphate pathway; PUFA: polyunsaturated fatty acid; RCD: regulated cell death; RNS: reactive nitrogen species; ROS: reactive oxygen species; RTAs: radical-trapping antioxidants; UPS: ubiquitin-proteasome system; UTR: untranslated region.
Citation impact
- FWCI
- 91.24
- Percentile
- 100%
- References
- 248
Authors
5- XCXin Chen
Southwestern Medical Center, Southwestern Medical Center, The University of Texas Southwestern Medical Center, Guangzhou Medical University
- JLJingbo Li
Southwestern Medical Center, Southwestern Medical Center, The University of Texas Southwestern Medical Center
- RKRui Kang
Southwestern Medical Center, Southwestern Medical Center, The University of Texas Southwestern Medical Center
- DJDaniel J. Klionsky
University of Michigan
- DTDaolin TangCorresponding
Southwestern Medical Center, Southwestern Medical Center, The University of Texas Southwestern Medical Center, Guangzhou Medical University
Topics & keywords
- Biology
- GPX4
- Biochemistry
- Cell biology
- Reactive oxygen species
- Lipid peroxidation
- Programmed cell death
- Pentose phosphate pathway
- Good health and well-being