reviewPharmaceuticsSep 9, 2020GOLD OA

Transfersomes: A Promising Nanoencapsulation Technique for Transdermal Drug Delivery

Chulalongkorn University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Transdermal delivery systems have gained much interest in recent years owing to their advantages compared to conventional oral and parenteral delivery systems. They are noninvasive and self-administered delivery systems that can improve patient compliance and provide a controlled release of the therapeutic agents. The greatest challenge of transdermal delivery systems is the barrier function of the skin's outermost layer. Molecules with molecular weights greater than 500 Da and ionized compounds generally do not pass through the skin. Therefore, only a limited number of drugs are capable of being administered by this route. Encapsulating the drugs in transfersomes are one of the potential approaches to…

Citation impact

494
total citations
FWCI
20.10
Percentile
100%
References
159
Citations per year

Authors

3

Topics & keywords

Keywords
  • Transdermal
  • Liposome
  • Drug delivery
  • Drug
  • Patient compliance
  • Pharmacology
  • Amphiphile
  • Delivery system
UN Sustainable Development Goals
  • Good health and well-being
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