Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial

Powles, Thomas; Heijden, Michiel S. van der; Castellano, Daniel; Galsky, Matthew D.; Loriot, Yohann; Petrylak, Daniel P.; Ogawa, Osamu; Park, Se Hoon; Lee, Jae‐Lyun; Giorgi, Ugo De; Bögemann, Martin; Bamias, Aristotelis; Eigl, Bernhard J.; Gurney, Howard; Mukherjee, Som D.; Fradet, Yves; Skoneczna, Iwona; Tsiatas, Marinos; Novikov, Andrey; Suárez, Cristina; Fay, André P.; Durán, Ignacio; Necchi, Andrea; Wildsmith, Sophie; He, Philip; Angra, Natasha; Gupta, Ashok; Levin, Wendy J.; Bellmunt, Joaquim; Park, Se Hoon; Heijden, Michiel S. van der; Necchi, Andrea; Castellano, Daniel; Bamias, Aristotelis; Lee, Jae‐Lyun; Giorgi, Ugo De; Bögemann, Martin; Eigl, Bernhard J.; Tsiatas, Marinos; Powles, Thomas; Novikov, Andrey; Skoneczna, Iwona; Mukherjee, Som D.; Suárez, Cristina; Westgeest, Hans M.; Fradet, Yves; Fléchon, Aude; Ou, Yen‐Chuan; Park, Inkeun; Matveev, Vsevolod; Pérez‐Valderrama, Begoña; Cheng, Susanna; Frank, Stephen Jay; Gurney, Howard; Anido, Urbano; Hamzaj, Alketa; Retz, Margitta; Sridhar, Srikala S.; Scagliotti, Giorgio V.; Voortman, Jens; Alekseev, B. Yа.; Alyasova, Anna; Komyakov, B. K.; Dumez, Herlinde; Pavic, Michel; Kimura, Go; Mizokami, Atsushi; Osanto, Susanne; Arranz, José Ángel; Piersma, Djura; Shin, Sang Joon; Karyakin, O. B.; Delgado, Ignacio; González, José Luis; Pang, See‐Tong; Tran, Anna; Lipatov, Oleg; Su, Wen-Pin; Flaig, Thomas W.; Alva, Ajjai; Kyong, Hwa Park; Kopyltsov, Evgeny; Almagro, Elena; Doménech, M.; Chang, Yen‐Hwa; Sautois, Brieuc; Ravaux, Andre; Aravantinos, Gerasimos; Georgoulias, V.; Mulder, Sasja F.; Kim, Yu Jung; Kater, Fabio; Chevreau, Christine; Tagawa, Scott T.; Zalewski, Paweł; Joly, Florence; Loriot, Yohann; Hatiboglu, Gencay; Gianni, Luca; Morelli, Franco; Tambaro, Rosa; Hashimoto, Yasuhiro; Носов, А. К.; Font, Albert; Rodríguez‐Vida, Alejo; Jones, Robert; Vasudev, Naveen; Srinivas, Sandhya; Zhang, Jingsong; Gil, Thierry; Finch, Daygen L.; Grimm, Marc‐Oliver; Su, Yu‐Li; Chowdhury, Simon; Hocking, Christopher; Plas, Eugen; North, Scott; Jensen, Niels Viggo; Théodore, C; Imkamp, Florian; Peer, Avivit; Kobayashi, Takashi; Sakai, Hideki; Sassa, Naoto; Yoshimura, Kazuhiro; Aarts, Maureen J.B.; Castro, Ana Ferreira; Topuzov, M. E.; Rodrı́guez, Juan F.; Vazquez, Federico Jose; Tsai, Yu‐Chieh; Crabb, Simon J.; Hussain, Syed A.; Bendell, Johanna C.; Gross‐Goupil, Marine; Gravis, Gwénaëlle; Berger, Raanan; Statsenko, Galina; Evans, Linda; Drakaki, Alexandra; Somer, Bradley G.; Davis, Ian D.; Lynam, James; Borges, Giuliano; Dettino, Aldo Lourenço Abbade; Fay, André P.; Martins, Graziella; Zucca, Luis Eduardo Rosa; Agerbæk, Mads; Kalofonos, Haralambos; Rosenbaum, Eli; Enokida, Hideki; Kikukawa, Hiroaki; Nishimura, Kazuo; Tamada, Satoshi; Uemura, Motohide; Lopez, Yamil; Gietema, Jourik A.; Słojewski, Marcin; Fernandes, Isabel; Smolin, Alexey; Mazhar, Danish; Kalebasty, Arash Rezazadeh; Carthon, Bradley Curtis; Loidl, Wolfgang; Franke, Fábio; Girotto, Gustavo; Alimohamed, Nimira; Macfarlane, Robyn Jane; Pappot, Helle; Niegisch, Guenter; Mavroudis, Dimitriοs; Sella, Avishay; Porta, Camillo; Ebara, Shin; Nakamura, Motonobu; Obara, Wataru; Okuno, Norihiko; Shinohara, Nobuo; Sugimoto, Mikio; Suzuki, Akitaka; Tokuda, Noriaki; Uemura, Hiroji; Yamaguchi, Akito; Ramirez, Francisco; Różanowski, Paweł; Wiechno, Paweł; Keam, Bhumsuk; Kislov, Nikolay; Plaksin, Denis; Çiçin, İrfan; Kumar, Satish; Galsky, Matthew D.; Petrylak, Daniel P.; Rosales, Joseph; Vaishampayan, Ulka N.; Culine, Stéphane; Papandreou, Christos N.; Nara, Taketoshi; Erman, Mustafa; Kreiger, Laurence; Janoski, Juliana; Rosa, Diogo Martins; Siqueira, Mariana Bruno; Canil, Christina; Sengeløv, Lisa; Tourani, Jean‐Marc; Arai, Gaku; Hashine, Katsuyoshi; Kawakita, Mutsushi; Nakaigawa, Noboru; Nomi, Hayahito; Shiina, Hiroaki; Suzuki, Hiroyoshi; Yonese, Junji; Kuri, Roberto; Macedo, Eleazar Omar; Rivera, Samuel; Prieto, Alberto Villalobos; Polakiewicz-Gilowska, Anna; Zaucha, Renata; Lopes, Fábio; Ponomarev, Roman; Pomerantz, Mark M.; Shariat, Shahrokh F.; Luk, Cynthia T.; Leśniewski-Kmak, Krzysztof

doi:10.1016/s1470-2045(20)30541-6

articleThe Lancet OncologySep 21, 2020BRONZE OA

Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial

TPThomas PowlesMSMichiel S. van der HeijdenDCDaniel CastellanoMDMatthew D. Galsky YLYohann Loriot

Queen Mary University of London · Dutch Cancer Society · +36 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

494

total citations

FWCI: 67.02
Percentile: 100%
References: 25

Citations per year

Authors

227

TP
Thomas PowlesCorresponding
Queen Mary University of London
MS
Michiel S. van der Heijden
Dutch Cancer Society, The Netherlands Cancer Institute
DC
Daniel Castellano
Hospital Universitario 12 De Octubre
MD
Matthew D. Galsky
Mount Sinai Hospital, Tisch Hospital
YL
Yohann Loriot
Inserm, Université Paris-Saclay, Institut Gustave Roussy

Topics & keywords

Topics

Keywords

Durvalumab
Medicine
Tremelimumab
Chemotherapy
Metastatic Urothelial Carcinoma
Oncology
Open label
Internal medicine

No related works found for this paper.