Cellular uptake and retention of nanoparticles: Insights on particle properties and interaction with cellular components

The utilization of nanomaterials in the biological and medical field is quickly progressing, particularly in areas where traditional diagnostics and treatment approaches have limited success. The success of nanomaterials in medical products such as biomedical implants, wound dressings and drug delivery systems rely upon their effective interaction between the extracellular matrix, cells, and intracellular components. Upon contact with mammalian cells, nanoparticles (NPs) begin to interact with the extracellular matrix, cell membrane, cytoplasmic proteins, nucleus, and other cellular organelles, which result in nanoparticle internalization and subsequent cellular responses. Such responses elicited by the…

• QF
  Qatar Foundation

  Award: NPRP9-144-3-021
• FN
  Fonds National de la Recherche Luxembourg
• QN
  Qatar National Research Fund

  Award: NPRP9-144-3-021