Case Series of Multisystem Inflammatory Syndrome in Adults Associated with SARS-CoV-2 Infection — United Kingdom and United States, March–August 2020

During the course of the coronavirus disease 2019 (COVID-19) pandemic, reports of a new multisystem inflammatory syndrome in children (MIS-C) have been increasing in Europe and the United States (1-3). Clinical features in children have varied but predominantly include shock, cardiac dysfunction, abdominal pain, and elevated inflammatory markers, including C-reactive protein (CRP), ferritin, D-dimer, and interleukin-6 (1). Since June 2020, several case reports have described a similar syndrome in adults; this review describes in detail nine patients reported to CDC, seven from published case reports, and summarizes the findings in 11 patients described in three case series in peer-reviewed journals (4-6).…

• P
  Pfizer
• NY
  New York City Department of Health and Mental Hygiene
• MD
  Minnesota Department of Health
• MG
  Massachusetts General Hospital
• UO
  University of Miami
• EU
  Emory University
• UO
  University of Southern Maine
• BI
  Broad Institute
• LD
  Louisiana Department of Health
• NT
  Nabriva Therapeutics
• NI
  National Institutes of Health
• OR
  Oak Ridge Institute for Science and Education
• SO
  School of Medicine, Emory University
• LM
  Leonard M. Miller School of Medicine