Detection of mobile genetic elements associated with antibiotic resistance in Salmonella enterica using a newly developed web tool: MobileElementFinder
MHMarkus Hans Kristofer JohanssonVBValeria BortolaiaSTSupathep TansirichaiyaFMFrank M. AarestrupAPAdam P. Roberts
Technical University of Denmark · UiT The Arctic University of Norway · +1 more institution
Indexed incrossrefpubmed
Abstract
Objectives
Antimicrobial resistance (AMR) in clinically relevant bacteria is a growing threat to public health globally. In these bacteria, antimicrobial resistance genes are often associated with mobile genetic elements (MGEs), which promote their mobility, enabling them to rapidly spread throughout a bacterial community.
Methods
The tool MobileElementFinder was developed to enable rapid detection of MGEs and their genetic context in assembled sequence data. MGEs are detected based on sequence similarity to a database of 4452 known elements augmented with annotation of resistance genes, virulence factors and detection of plasmids.
Citation impact
686
total citations
- FWCI
- 46.86
- Percentile
- 100%
- References
- 47
Citations per year
Authors
6Topics & keywords
Topics
Keywords
- Salmonella enterica
- Salmonella
- Mobile genetic elements
- Antibiotic resistance
- Microbiology
- Antibiotics
- Biology
- Computational biology
UN Sustainable Development Goals
- Good health and well-being
No related works found for this paper.