articleJournal of Antimicrobial ChemotherapyAug 25, 2020HYBRID OA

Detection of mobile genetic elements associated with antibiotic resistance in Salmonella enterica using a newly developed web tool: MobileElementFinder

Technical University of Denmark · UiT The Arctic University of Norway · +1 more institution

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Abstract

Objectives

Antimicrobial resistance (AMR) in clinically relevant bacteria is a growing threat to public health globally. In these bacteria, antimicrobial resistance genes are often associated with mobile genetic elements (MGEs), which promote their mobility, enabling them to rapidly spread throughout a bacterial community.

Methods

The tool MobileElementFinder was developed to enable rapid detection of MGEs and their genetic context in assembled sequence data. MGEs are detected based on sequence similarity to a database of 4452 known elements augmented with annotation of resistance genes, virulence factors and detection of plasmids.

Citation impact

686
total citations
FWCI
46.86
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100%
References
47
Citations per year

Authors

6

Topics & keywords

Keywords
  • Salmonella enterica
  • Salmonella
  • Mobile genetic elements
  • Antibiotic resistance
  • Microbiology
  • Antibiotics
  • Biology
  • Computational biology
UN Sustainable Development Goals
  • Good health and well-being
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