articleJournal of Medicinal ChemistryOct 15, 2020BRONZE OA

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Pfizer (United States) · Southern Research Institute

PubMed
Indexed incrossrefdatacitepubmed

Abstract

With suitable pharmaceutical properties to warrant further development as an intravenous treatment for COVID-19.

Citation impact

530
total citations
FWCI
9.65
Percentile
100%
References
45
Citations per year

Authors

24

Topics & keywords

Keywords
  • Coronavirus
  • Chemistry
  • Proteases
  • Polyproteins
  • Protease
  • Cleavage (geology)
  • Cysteine protease
  • Virology
UN Sustainable Development Goals
  • Good health and well-being
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