reviewPhysiological GenomicsSep 29, 2020HYBRID OA

The COVID-19 pandemic: a global health crisis

University of Toledo · Imaging Center

PubMed
Indexed incrossrefpubmed

Abstract

The novel coronavirus SARS-CoV-2 was identified as the causative agent for a series of atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019. The disease SARS-CoV-2, termed COVID-19, was officially declared a pandemic by the World Health Organization on March 11, 2020. SARS-CoV-2 contains a single-stranded, positive-sense RNA genome surrounded by an extracellular membrane containing a series of spike glycoproteins resembling a crown. COVID-19 infection results in diverse symptoms and morbidity depending on individual genetics, ethnicity, age, and geographic location. In severe cases, COVID-19 pathophysiology includes destruction of lung epithelial cells, thrombosis,…

Citation impact

522
total citations
FWCI
9.09
Percentile
100%
References
85
Citations per year

Authors

3

Topics & keywords

Keywords
  • Cytokine storm
  • ARDS
  • Immunology
  • Population
  • Biology
  • Pandemic
  • Disease
  • Pulmonary fibrosis
UN Sustainable Development Goals
  • Good health and well-being
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