Characteristics of SARS-CoV-2 and COVID-19
Chinese Academy of Sciences · Wuhan Institute of Virology · +1 more institution
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety. In this Review, we describe the basic virology of SARS-CoV-2, including genomic characteristics and receptor use, highlighting its key difference from previously known coronaviruses. We summarize current knowledge of clinical, epidemiological and pathological features of COVID-19, as well as recent progress in animal models and antiviral treatment approaches for SARS-CoV-2 infection. We also discuss the potential wildlife…
Citation impact
- FWCI
- 101.08
- Percentile
- 100%
- References
- 173
Authors
4- BHBen HuCorresponding
Chinese Academy of Sciences, Wuhan Institute of Virology
- HGHua Guo
Chinese Academy of Sciences, Wuhan Institute of Virology, University of Chinese Academy of Sciences
- PZPeng Zhou
Chinese Academy of Sciences, Wuhan Institute of Virology
- ZSZheng‐Li Shi
Chinese Academy of Sciences, Wuhan Institute of Virology
Topics & keywords
- Coronavirus
- Pandemic
- Biology
- Virology
- Coronavirus disease 2019 (COVID-19)
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Disease
- Severe acute respiratory syndrome coronavirus
- Good health and well-being