Mortality in biopsy-confirmed nonalcoholic fatty liver disease: results from a nationwide cohort
Harvard University · Massachusetts General Hospital · +6 more institutions
Abstract
Objective Population-based data are lacking regarding the risk of overall and cause-specific mortality across the complete histological spectrum of non-alcoholic fatty liver disease (NAFLD). Design This nationwide, matched cohort study included all individuals in Sweden with biopsy-confirmed NAFLD (1966 to 2017; n=10 568). NAFLD was confirmed histologically from all liver biopsies submitted to Sweden’s 28 pathology departments, after excluding other etiologies of liver disease, and further categorised as, simple steatosis, non-fibrotic steatohepatitis (NASH), non-cirrhotic fibrosis and cirrhosis. NAFLD cases were matched to ≤5 general population comparators by age, sex, calendar year and county (n=49 925).…
Citation impact
- FWCI
- 47.76
- Percentile
- 100%
- References
- 43
Authors
5- TGTracey G. Simon
Harvard University, Massachusetts General Hospital
- BRBjörn Roelstraete
Stockholm County Council, Karolinska Institutet
- HKHamed Khalili
Harvard University, Massachusetts General Hospital
- HHHannes Hagström
Karolinska University Hospital
- JFJonas F. LudvigssonCorresponding
University of Nottingham, Stockholm County Council, Karolinska Institutet, Örebro University Hospital, Columbia University
Topics & keywords
- Medicine
- Internal medicine
- Gastroenterology
- Cirrhosis
- Nonalcoholic fatty liver disease
- Steatohepatitis
- Fatty liver
- Steatosis
- Good health and well-being