Accurate brain age prediction with lightweight deep neural networks
Wellcome Centre for Integrative Neuroimaging · University of Oxford · +2 more institutions
Abstract
Deep learning has huge potential for accurate disease prediction with neuroimaging data, but the prediction performance is often limited by training-dataset size and computing memory requirements. To address this, we propose a deep convolutional neural network model, Simple Fully Convolutional Network (SFCN), for accurate prediction of brain age using T1-weighted structural MRI data. Compared with other popular deep network architectures, SFCN has fewer parameters, so is more compatible with small dataset size and 3D volume data. The network architecture was combined with several techniques for boosting performance, including data augmentation, pre-training, model regularization, model ensemble and prediction…
Citation impact
- FWCI
- 33.87
- Percentile
- 100%
- References
- 64
Authors
5- HPHan PengCorresponding
Wellcome Centre for Integrative Neuroimaging, University of Oxford, Radboud University Nijmegen, Oxford Research Group
- WGWeikang Gong
University of Oxford, Wellcome Centre for Integrative Neuroimaging
- CFChristian F. Beckmann
Wellcome Centre for Integrative Neuroimaging, Radboud University Nijmegen, University of Oxford
- AVAndrea Vedaldi
University of Oxford, Oxford Research Group
- SMStephen M. Smith
Wellcome Centre for Integrative Neuroimaging, University of Oxford
Topics & keywords
- Computer science
- Deep learning
- Artificial intelligence
- Convolutional neural network
- Machine learning
- Boosting (machine learning)
- Artificial neural network
- Neuroimaging
Funding
- ASAutism Speaks
- WTWellcome TrustAwards: 203139/Z/16/Z, 215573/Z/19/Z, 203139
- EFEuropean Federation of Pharmaceutical Industries and AssociationsAwards: 777394, AIMS-2-TRIALS
- SFSimons Foundation Autism Research Initiative
- NINational Institute for Health and Care ResearchAward: 203139/Z/16/Z
- ECEuropean CommissionAwards: 203139/Z/16/Z, 777394
- TWThe Wellcome Trust DBT India Alliance
- IMInnovative Medicines InitiativeAwards: 777394, AIMS-2-TRIALS
- MRMedical Research CouncilAward: MC_PC_17228
- OMOxford Martin School, University of Oxford
- H2Horizon 2020
- BRBiomedical Research Council
- NONIHR Oxford Biomedical Research CentreAward: 203139/Z/16/Z