reviewAdvanced MaterialsOct 16, 2020Closed access

Recent Advances in Nanomaterial‐Assisted Combinational Sonodynamic Cancer Therapy

University of Science and Technology of China · Chinese Academy of Sciences · +1 more institution

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Abstract

Abstract Ultrasound (US)‐triggered sonodynamic therapy (SDT), as a promising noninvasive therapeutic modality, has received ever‐increasing attention in recent years. Its specialized chemical agents, named sonosensitizers, are activated by low‐intensity US to produce lethal reactive oxygen species (ROS) for oncotherapy. Compared with phototherapeutic strategies, SDT provides many noteworthy opportunities and benefits, such as deeper penetration depth, absence of phototoxicity, and fewer side effects. Nevertheless, previous studies have also demonstrated its intrinsic limitations. Thanks to the facile engineering nature of nanotechnology, numerous novel nanoplatforms are being applied in this emerging field to…

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