reviewNew England Journal of MedicineOct 14, 2020Closed access

Autophagy in Human Diseases

Howard Hughes Medical Institute · The University of Tokyo · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Autophagy is a complex process of intracellular degradation of senescent or malfunctioning organelles. Dysregulated autophagy is associated with certain cancers, neurodegenerative diseases, immune dysfunction, and aging. Therapies aimed at regulating autophagy are being developed.

Citation impact

1,136
total citations
FWCI
98.32
Percentile
100%
References
86
Citations per year

Authors

2

Topics & keywords

Keywords
  • Autophagy
  • Intracellular
  • Medicine
  • Organelle
  • Immune system
  • Cell biology
  • Immunology
  • Biology
UN Sustainable Development Goals
  • Good health and well-being
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