The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions

The BioGRID (Biological General Repository for Interaction Datasets, thebiogrid.org) is an open-access database resource that houses manually curated protein and genetic interactions from multiple species including yeast, worm, fly, mouse, and human. The ~1.93 million curated interactions in BioGRID can be used to build complex networks to facilitate biomedical discoveries, particularly as related to human health and disease. All BioGRID content is curated from primary experimental evidence in the biomedical literature, and includes both focused low-throughput studies and large high-throughput datasets. BioGRID also captures protein post-translational modifications and protein or gene interactions with…

• GC
  Genome Canada
• NI
  National Institutes of Health

  Awards: R01OD010929, OT3TR002026
• SU
  Stand Up To Cancer
• CI
  Canadian Institutes of Health Research

  Awards: FDN-167277, FDN‐167277
• NC
  National Center for Advancing Translational Sciences

  Award: OT3TR002026