reviewMicroorganismsNov 1, 2020GOLD OA

The Influence of Probiotics on the Firmicutes/Bacteroidetes Ratio in the Treatment of Obesity and Inflammatory Bowel disease

University of Ljubljana · Jožef Stefan Institute

PubMed
Indexed incrossrefdoajpubmed

Abstract

The two most important bacterial phyla in the gastrointestinal tract, Firmicutes and Bacteroidetes, have gained much attention in recent years. The Firmicutes/Bacteroidetes (F/B) ratio is widely accepted to have an important influence in maintaining normal intestinal homeostasis. Increased or decreased F/B ratio is regarded as dysbiosis, whereby the former is usually observed with obesity, and the latter with inflammatory bowel disease (IBD). Probiotics as live microorganisms can confer health benefits to the host when administered in adequate amounts. There is considerable evidence of their nutritional and immunosuppressive properties including reports that elucidate the association of probiotics with the F/B…

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1,884
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62.18
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100%
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108
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Authors

3

Topics & keywords

Keywords
  • Firmicutes
  • Bacteroidetes
  • Dysbiosis
  • Obesity
  • Inflammatory bowel disease
  • Gut flora
  • Lactobacillus
  • Immunology
UN Sustainable Development Goals
  • Zero hunger
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