Physical traits of cancer
Boston University · Harvard University · +1 more institution
Abstract
The role of the physical microenvironment in tumor development, progression, metastasis, and treatment is gaining appreciation. The emerging multidisciplinary field of the physical sciences of cancer is now embraced by engineers, physicists, cell biologists, developmental biologists, tumor biologists, and oncologists attempting to understand how physical parameters and processes affect cancer progression and treatment. Discoveries in this field are starting to be translated into new therapeutic strategies for cancer. In this Review, we propose four physical traits of tumors that contribute to tumor progression and treatment resistance: (i) elevated solid stresses (compression and tension), (ii) elevated…
Citation impact
- FWCI
- 43.69
- Percentile
- 100%
- References
- 150
Authors
3Topics & keywords
- Cancer
- Biology
- Computational biology
- Evolutionary biology
- Genetics
- Good health and well-being