articleNucleic Acids ResearchOct 14, 2020GOLD OA

DBAASP v3: database of antimicrobial/cytotoxic activity and structure of peptides as a resource for development of new therapeutics

National Institutes of Health · National Institute of Allergy and Infectious Diseases

PubMed
Indexed incrossrefdoajpubmed

Abstract

The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is an open-access, comprehensive database containing information on amino acid sequences, chemical modifications, 3D structures, bioactivities and toxicities of peptides that possess antimicrobial properties. DBAASP is updated continuously, and at present, version 3.0 (DBAASP v3) contains >15 700 entries (8000 more than the previous version), including >14 500 monomers and nearly 400 homo- and hetero-multimers. Of the monomeric antimicrobial peptides (AMPs), >12 000 are synthetic, about 2700 are ribosomally synthesized, and about 170 are non-ribosomally synthesized. Approximately 3/4 of the entries were added after the initial release of…

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Authors

10

Topics & keywords

Keywords
  • Biology
  • Antimicrobial peptides
  • Antimicrobial
  • Computational biology
  • Database
  • Bioinformatics
  • Microbiology
  • Computer science
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