Risk factors for severe and critically ill COVID‐19 patients: A review

The pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an unprecedented global social and economic impact, and high numbers of deaths. Many risk factors have been identified in the progression of COVID-19 into a severe and critical stage, including old age, male gender, underlying comorbidities such as hypertension, diabetes, obesity, chronic lung diseases, heart, liver and kidney diseases, tumors, clinically apparent immunodeficiencies, local immunodeficiencies, such as early type I interferon secretion capacity, and pregnancy. Possible complications include acute kidney injury, coagulation disorders, thoromboembolism. The…

• NS
  National Science Foundation
• A
  AstraZeneca
• S
  Sanofi
• RP
  Regeneron Pharmaceuticals
• SN
  Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
• IP
  Idorsia Pharmaceuticals
• A
  Allergopharma