Isolation and characterization of exosomes for cancer research

Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins, nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes participate in intercellular communication and act as important molecular vehicles in the regulation of numerous physiological and pathological processes, including cancer development. Exosomes are released by various cell types under both normal and pathological conditions, and they can be found in multiple bodily fluids. Moreover, exosomes carrying a wide variety of important macromolecules provide a window into altered cellular or tissue states. Their presence in biological fluids renders them an attractive, minimally invasive approach…

• NN
  National Natural Science Foundation of China

  Awards: 81672820, 2017YFC0908402, 81702857, 81940074, 81772563
• CP
  China Postdoctoral Science Foundation

  Award: 2017M611459
• NK
  National Key Research and Development Program of China

  Awards: 2017YFC0908402, 2017YFC1308604 and 2017YFC0908402, 2017YFC1308604
• PO
  Program of Shanghai Academic Research Leader

  Award: 20XD1400900