Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: A systematic review and meta-analysis

Studies have suggested that there is increased risk of thromboembolism (TE) associated with coronavirus disease 2019 . However, overall arterial and venous TE rates of COVID-19 and effect of TE on COVID-19 mortality is unknown.

We did a systematic review and meta-analysis of studies evaluating TE in COVID-19. We searched PubMed, Cochrane, and Embase for studies published up to June 12, 2020. Random effects models were used to produce summary TE rates and odds ratios (OR) of mortality in COVID-19 patients with TE compared to those without TE. Heterogeneity was quantified with I 2 .