Exosome-based immunotherapy: a promising approach for cancer treatment
Central South University · Xiangya Hospital Central South University
Abstract
In the era of the rapid development of cancer immunotherapy, there is a high level of interest in the application of cell-released small vesicles that stimulate the immune system. As cell-derived nanovesicles, exosomes show great promise in cancer immunotherapy because of their immunogenicity and molecular transfer function. The cargoes carried on exosomes have been recently identified with improved technological advances and play functional roles in the regulation of immune responses. In particular, exosomes derived from tumor cells and immune cells exhibit unique composition profiles that are directly involved in anticancer immunotherapy. More importantly, exosomes can deliver their cargoes to targeted cells…
Citation impact
- FWCI
- 19.92
- Percentile
- 100%
- References
- 188
Authors
4- ZXZhijie XuCorresponding
Central South University, Xiangya Hospital Central South University
- SZShuangshuang Zeng
Central South University, Xiangya Hospital Central South University
- ZGZhicheng Gong
Central South University, Xiangya Hospital Central South University
- YYYuanliang Yan
Central South University, Xiangya Hospital Central South University
Topics & keywords
- Microvesicles
- Immunotherapy
- Exosome
- Immune system
- Cancer immunotherapy
- Cancer
- Immunogenicity
- Cancer research
- Good health and well-being
Funding
- NNNational Natural Science Foundation of ChinaAwards: 81703036, 2019JJ50932, 81803035, 2020M672521, 2020JJ5934
- CSCentral South University
- CPChina Postdoctoral Science FoundationAwards: 81803035, 2019JJ50932, 2020M672521, 2017M610510
- NSNatural Science Foundation of Hunan ProvinceAwards: 2019JJ50932, 2020JJ5934
- PSPostdoctoral Science Foundation of Central South UniversityAward: 248485
- PRPostdoctoral Research Foundation of ChinaAwards: 2017M610510, 2020M672521
- XHXiangya Hospital, Central South University