Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ
University of California, Berkeley · Tsinghua University · +3 more institutions
Abstract
Tetrameric immune receptors Nucleotide-binding/leucine-rich repeat (NLR) immune receptors detect pathogen effectors and trigger a plant's immune response. Two groups have now defined the structures of two NLRs that carry Toll-like interleukin-1 receptor (TIR) domains (TIR-NLRs) (see the Perspective by Tian and Li). Ma et al. studied the Arabidopsis thaliana TIR-NLR RPP1 (recognition of Peronospora parasitica 1) and its response to effectors from an oomycete pathogen. Martin et al. studied the Nicotiana benthamiana TIR-NLR ROQ1 (recognition of XopQ 1) and its response to the Xanthomonas effector. Both groups found that these TIR-NLRs formed tetramers that, when activated by binding to the pathogen effector,…
Citation impact
- FWCI
- 67.51
- Percentile
- 100%
- References
- 58
Authors
8- RMRaoul MartinCorresponding
University of California, Berkeley
- TQTiancong QiCorresponding
University of California, Berkeley, Tsinghua University
- HZHaibo Zhang
Tsinghua University
- FLFurong Liu
Innovative Genomics Institute, University of California, Berkeley
- MKMiles King
Innovative Genomics Institute, University of California, Berkeley
Topics & keywords
- Effector
- Biology
- Pathogen
- Nicotiana benthamiana
- Immune system
- Xanthomonas
- Immune receptor
- Arabidopsis thaliana