articleScienceDec 4, 2020Closed access

Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme

MSMa ShouCaiDLDmitry LapinJLJie LiuYSYue SunWSWen Song

Center for Life Sciences · Max Planck Institute for Plant Breeding Research · +2 more institutions

PubMed
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Abstract

Tetrameric immune receptors Nucleotide-binding/leucine-rich repeat (NLR) immune receptors detect pathogen effectors and trigger a plant's immune response. Two groups have now defined the structures of two NLRs that carry Toll-like interleukin-1 receptor (TIR) domains (TIR-NLRs) (see the Perspective by Tian and Li). Ma et al. studied the Arabidopsis thaliana TIR-NLR RPP1 (recognition of Peronospora parasitica 1) and its response to effectors from an oomycete pathogen. Martin et al. studied the Nicotiana benthamiana TIR-NLR ROQ1 (recognition of XopQ 1) and its response to the Xanthomonas effector. Both groups found that these TIR-NLRs formed tetramers that, when activated by binding to the pathogen effector,…

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500
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100%
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Authors

14

Topics & keywords

Topics
Keywords
  • Effector
  • Biology
  • Nicotiana benthamiana
  • Pathogen
  • Immune system
  • Immune receptor
  • Xanthomonas
  • Pathogen-associated molecular pattern
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