reviewFrontiers in Cellular and Infection MicrobiologyNov 25, 2020GOLD OA

SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development

MWMei-Yue WangRZRong ZhaoLGLijuan GaoXGXuefei GaoDWDeping Wang

Shanxi Medical University

PubMed
Indexed incrossrefdoajpubmed

Abstract

The pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been posing great threats to the world in many aspects. Effective therapeutic and preventive approaches including drugs and vaccines are still unavailable although they are in development. Comprehensive understandings on the life logic of SARS-CoV-2 and the interaction of the virus with hosts are fundamentally important in the fight against SARS-CoV-2. In this review, we briefly summarized the current advances in SARS-CoV-2 research, including the epidemic situation and epidemiological characteristics of the caused disease COVID-19. We further discussed the biology of SARS-CoV-2, including the origin, evolution, and…

Citation impact

904
total citations
FWCI
18.09
Percentile
100%
References
137
Citations per year

Authors

6

Topics & keywords

Topics
Keywords
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Pandemic
  • Coronavirus disease 2019 (COVID-19)
  • Mechanism (biology)
  • Coronavirus
  • 2019-20 coronavirus outbreak
  • Biology
  • Virology
UN Sustainable Development Goals
  • Good health and well-being
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