articleScientific ReportsNov 25, 2020GOLD OA

VolcaNoseR is a web app for creating, exploring, labeling and sharing volcano plots

Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital · University of Amsterdam · +1 more institution

PubMed
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Abstract

Comparative genome- and proteome-wide screens yield large amounts of data. To efficiently present such datasets and to simplify the identification of hits, the results are often presented in a type of scatterplot known as a volcano plot, which shows a measure of effect size versus a measure of significance. The data points with the largest effect size and a statistical significance beyond a user-defined threshold are considered as hits. Such hits are usually annotated in the plot by a label with their name. Volcano plots can represent ten thousands of data points, of which typically only a handful is annotated. The information of data that is not annotated is hardly or not accessible. To simplify access to the…

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Authors

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Topics & keywords

Keywords
  • Plot (graphics)
  • Computer science
  • Web application
  • Measure (data warehouse)
  • Data mining
  • Identification (biology)
  • Information retrieval
  • World Wide Web
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