Prescribed drugs containing nitrogen heterocycles: an overview
MMMajid M. HeraviVZVahideh Zadsirjan
Indexed incrossrefdoajpubmed
Abstract
Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all biologically active compounds are heterocycles or comprise a heterocycle and most frequently, nitrogen heterocycles as a backbone in their complex structures. These facts disclose and emphasize the vital role of heterocycles in modern drug design and drug discovery. In this review, we try to present a comprehensive overview of top prescribed drugs containing nitrogen heterocycles, describing their pharmacological properties, medical applications and their selected synthetic pathways. It is worth mentioning that the reported…
Citation impact
1,109
total citations
- FWCI
- 48.45
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- 100%
- References
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Citations per year
Authors
2- MMMajid M. HeraviCorresponding
Alzahra University
- VZVahideh Zadsirjan
Alzahra University
Topics & keywords
Topics
Keywords
- Nitrogen
- Chemistry
- Combinatorial chemistry
- Environmental chemistry
- Organic chemistry
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